CAN DECALCIFIED FREEZE-DRIED BONE ALLOGRAFT PROMOTE BONE HEALING; PRELIMINARY RESULTS FROM SINGLE CENTRE
Authors:
Asterios Antoniou, Georgios Chatziantoniou, Anestis Chrysostomidis, Antonios Saramantos, Vaia-Aikaterini Alexoudi, Ioannis Astreidis Sofianos, Konstantinos Paraskevopoulos, Konstantinos Vachtsevanos
Affiliation:
Department of Oral and Maxillofacial Surgery, Aristotle University of Thessaloniki, Thessaloniki, Greece
Doi: 10.54936/haoms242p60
ABSTRACT:
that originate from odontogenic tissues that occur in tooth-bearing regions of the jaws. After enucleation, bone remodelling is triggered to fill the bone defects. The aim of this study is to evaluate the ability of Decalcified Freeze-Dried Bone Allograft to enhance the wound healing process by assessing the inflammation process, and radiographic bone density pre- and postoperatively.
Materials and methods: Twenty-five patients with cysts were included in this study. All patients received enucleation of the cyst, removal of the underlying cause, and Decalcified Freeze- Dried Bone Allograft, to fill the bone defect. Radiographic bone density was assessed by analysing the housefield units in a computed tomography scan preoperative and postoperative 6 months later.
Results: Patients included in the study had a mean age of 45 years (range from 16 to 72). Male to female ratio was 5:1. Bone density was found significantly higher by measuring the change in housefield units pre- and postoperatively. Complication-wise, 3 patients had a surgical site infection, leading to bone graft removal.
Conclusion: Odontogenic cysts can create a plethora of bone defects after enucleation. The preliminary results that are depicted from this present study demonstrate that Decalcified Freeze-Dried Bone Allograft can promote bone remodelling and healing.
KEY WORDS:
Authors:
Asterios Antoniou, Georgios Chatziantoniou, Anestis Chrysostomidis, Antonios Saramantos, Vaia-Aikaterini Alexoudi, Ioannis Astreidis Sofianos, Konstantinos Paraskevopoulos, Konstantinos Vachtsevanos
Affiliation:
Department of Oral and Maxillofacial Surgery, Aristotle University of Thessaloniki, Thessaloniki, Greece
Doi: 10.54936/haoms242p60
ABSTRACT:
that originate from odontogenic tissues that occur in tooth-bearing regions of the jaws. After enucleation, bone remodelling is triggered to fill the bone defects. The aim of this study is to evaluate the ability of Decalcified Freeze-Dried Bone Allograft to enhance the wound healing process by assessing the inflammation process, and radiographic bone density pre- and postoperatively.
Materials and methods: Twenty-five patients with cysts were included in this study. All patients received enucleation of the cyst, removal of the underlying cause, and Decalcified Freeze- Dried Bone Allograft, to fill the bone defect. Radiographic bone density was assessed by analysing the housefield units in a computed tomography scan preoperative and postoperative 6 months later.
Results: Patients included in the study had a mean age of 45 years (range from 16 to 72). Male to female ratio was 5:1. Bone density was found significantly higher by measuring the change in housefield units pre- and postoperatively. Complication-wise, 3 patients had a surgical site infection, leading to bone graft removal.
Conclusion: Odontogenic cysts can create a plethora of bone defects after enucleation. The preliminary results that are depicted from this present study demonstrate that Decalcified Freeze-Dried Bone Allograft can promote bone remodelling and healing.
KEY WORDS: