Plexiform neurofibroma of the temporal area in a patient with von Recklinghausen disease A case report
Panayotis DAIS, Dipen PATEL, Kavin ANDI
Department of Oral and Maxillofacial Surgery (Consultant: Mr Kavin Andi), St. George’s Healthcare NHS Trust, London, UK
Hellenic Archives of Oral & Maxillofacial Surgery (2015) 1, 17-22
SUMMARY: A 25-year-old Caucasian gentleman was re- ferred to the maxillofacial department regarding a 6- month history of diffuse swelling in the left temporal re- gion. The patient first noticed the swelling after a sus- tained trauma on a roller-coaster, and is a known Neu- rofibromatosis type I (NF-I or von Recklinghausen’s dis- ease) carrier. Magnetic Resonance Imaging (MRI) scan revealed a superficial neurofibromatous lesion, believed to be plexiform neurofibroma. The lesion was treated by surgical decompression. Incisional biopsy of the tem- poral muscle confirmed a diagnosis of plexiform neurofi- broma. The patient has healed excellently with a good cosmetic result and no evidence of recurrence thus far.
KEY WORDS: neurofibromatosis, von Recklinghausen's, temple, plexiform neurofibroma.
REFERENCES
Arden-Holmes S, North K.: Treatment for Plexiform Neurofibromas in patients with NF-1. The Lancet – Oncology; 13: 1175-1176, 2012
Dave S, Farooq U, Civantos F.: Management of advanced laryngeal and hypopharyngeal plexiform neurofibroma in adults. American Jour- nal of Otolaryngology - Head and Neck Medicine and Surgery; 29: 279-283, 2008
Evans DG, Baser ME, McGaughran J, Sharif S, Howard E, Moran A: Ma- lignant peripheral nerve sheath tumours in neurofibromatosis 1. J. Med. Genet. 39 (5): 311–4, 2002.
Fletcher C: Peripheral neuroectodermal tumours. In: Diagnostic Histopathology of Tumours (ed 3). Churchill Livingstone Elsevier, 2007, Vol.2, pp 1736-1742
Kapadia B: Tumours of the Nervous System. In: Barnes L, Dekker M (eds). Surgical pathology of the Head and Neck (ed 2). New York, Basel, 2001, Vol.2, pp 795-808
Arden-Holmes S, North K.: Treatment for Plexiform Neurofibromas in patients with NF-1. The Lancet – Oncology; 13: 1175-1176, 2012
Dave S, Farooq U, Civantos F.: Management of advanced laryngeal and hypopharyngeal plexiform neurofibroma in adults. American Jour- nal of Otolaryngology - Head and Neck Medicine and Surgery; 29: 279-283, 2008
Evans DG, Baser ME, McGaughran J, Sharif S, Howard E, Moran A: Malignant peripheral nerve sheath tumours in neurofibromatosis 1. J. Med. Genet. 39 (5): 311–4, 2002.
Fletcher C: Peripheral neuroectodermal tumours. In: Diagnostic Histopathology of Tumours (ed 3). Churchill Livingstone Elsevier, 2007, Vol.2, pp 1736-1742
Kapadia B: Tumours of the Nervous System. In: Barnes L, Dekker M (eds). Surgical pathology of the Head and Neck (ed 2). New York, Basel, 2001, Vol.2, pp 795-808
Department of Oral and Maxillofacial Surgery (Consultant: Mr Kavin Andi), St. George’s Healthcare NHS Trust, London, UK
Hellenic Archives of Oral & Maxillofacial Surgery (2015) 1, 17-22
SUMMARY: A 25-year-old Caucasian gentleman was re- ferred to the maxillofacial department regarding a 6- month history of diffuse swelling in the left temporal re- gion. The patient first noticed the swelling after a sus- tained trauma on a roller-coaster, and is a known Neu- rofibromatosis type I (NF-I or von Recklinghausen’s dis- ease) carrier. Magnetic Resonance Imaging (MRI) scan revealed a superficial neurofibromatous lesion, believed to be plexiform neurofibroma. The lesion was treated by surgical decompression. Incisional biopsy of the tem- poral muscle confirmed a diagnosis of plexiform neurofi- broma. The patient has healed excellently with a good cosmetic result and no evidence of recurrence thus far.
KEY WORDS: neurofibromatosis, von Recklinghausen's, temple, plexiform neurofibroma.
REFERENCES
Arden-Holmes S, North K.: Treatment for Plexiform Neurofibromas in patients with NF-1. The Lancet – Oncology; 13: 1175-1176, 2012
Dave S, Farooq U, Civantos F.: Management of advanced laryngeal and hypopharyngeal plexiform neurofibroma in adults. American Jour- nal of Otolaryngology - Head and Neck Medicine and Surgery; 29: 279-283, 2008
Evans DG, Baser ME, McGaughran J, Sharif S, Howard E, Moran A: Ma- lignant peripheral nerve sheath tumours in neurofibromatosis 1. J. Med. Genet. 39 (5): 311–4, 2002.
Fletcher C: Peripheral neuroectodermal tumours. In: Diagnostic Histopathology of Tumours (ed 3). Churchill Livingstone Elsevier, 2007, Vol.2, pp 1736-1742
Kapadia B: Tumours of the Nervous System. In: Barnes L, Dekker M (eds). Surgical pathology of the Head and Neck (ed 2). New York, Basel, 2001, Vol.2, pp 795-808
Arden-Holmes S, North K.: Treatment for Plexiform Neurofibromas in patients with NF-1. The Lancet – Oncology; 13: 1175-1176, 2012
Dave S, Farooq U, Civantos F.: Management of advanced laryngeal and hypopharyngeal plexiform neurofibroma in adults. American Jour- nal of Otolaryngology - Head and Neck Medicine and Surgery; 29: 279-283, 2008
Evans DG, Baser ME, McGaughran J, Sharif S, Howard E, Moran A: Malignant peripheral nerve sheath tumours in neurofibromatosis 1. J. Med. Genet. 39 (5): 311–4, 2002.
Fletcher C: Peripheral neuroectodermal tumours. In: Diagnostic Histopathology of Tumours (ed 3). Churchill Livingstone Elsevier, 2007, Vol.2, pp 1736-1742
Kapadia B: Tumours of the Nervous System. In: Barnes L, Dekker M (eds). Surgical pathology of the Head and Neck (ed 2). New York, Basel, 2001, Vol.2, pp 795-808
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