Basal cell adenoma of the parotid Report of 3 cases
Eleni PARARA, Dimosthenis IGOUMENAKIS, Constantinos MOUROUZIS, Dimitrios MASTAGKAS, Christos EFTYCHIADIS, George RALLIS
Department of Oral and Maxillofacial Surgery, General Hospital of Attica “KAT” (Head: Dr Dr G. Rallis) Department of Pathology, General Hospital of Attica “KAT” (Head: Dr Kal. Diamantopoulou)
Hellenic Archives of Oral & Maxillofacial Surgery (2018) 3, 151-157
SUMMARY: We present 3 cases of basal cell adenoma of the parotid treated at our Department. All patients complained of a retromandibular lump with clinical traits of benign parotid tumors. Diagnostic workup in all cases included tomography scans and fine needle aspiration biopsy. The former depicted parotid tumors with benign characteristics. Basal cell adenoma (BCA) was the cytology report in one of the patients, later confirmed histo- pathologically, whereas for the other two patients, FNA yielded an inconclusive report. Management included superficial parotidectomy for two cases and subtotal parotidectomy for the remaining one. All patients had an uneventful recovery. BCA is a rare benign tumor of the salivary glands. It is treated with surgical excision, similarly to more common benign tumors. A subtype of BCA, the membranous BCA, is characterized by higher recurrence rate, malignant transformation and simultaneous or later occurrence in other salivary or dermal glands. It is therefore recommended, for patients with the membranous subtype of BCA, to be long term followed up by an oral and maxillofacial surgeon, as well as a dermatologist.
KEY WORDS: basal cell adenoma, monomorphic adenoma, parotid
REFERENCES
Chiu NC, Wu HM, Chou YH, Li WY, Chiou YY, Guo WY, Chang CY: Basal Cell Adenoma Versus Pleomorphic Adenoma of the Parotid Gland: CT Findings. American Journal of Roentgenology 189 (5): 254-261, 2007
de Araujo VC: Basal cell adenoma, In: Barnes L, Everson JW, Reichart P, Sidransky D, editors: World Health Organization classification of tumors. Pathology and genetics of head and neck tumors. Lyon: IARC 2005. pp. 261-2
Fenske C, Carter N, Banerjee P, Holden C: Brooke–Spiegler Syndrome Locus Assigned to 16q12-q13. Journal of Investigative Dermatol- ogy 114(5): 1057-1058, 2000
García RG, Cha SHN, Muñoz Guerra MF, Gamallo Amat C: Basal cell adenoma of the parotid gland. Case report and review of the lit- erature. Med Oral Patol Oral Cir Bucal 11: E206-9, 2006
Gregoire C: Salivary gland tumors: the parotid gland. In: Bagheri, Bell and Khan: Current therapy in Oral and Maxillofacial Surgery, El- sevier Saunders 2012, pp 450-60
Handra-Luca A: Basal cell adenoma. Pathology Outlines.com website. http://www.pathologyoutlines.com/topic/salivaryglandsbasalcel- ladenoma.html. Accessed June 13th, 2018
Jang M, Park D, Lee SR, Hahm CK, Kim Y, Kim Y, Park CK, Tae K, Park MH, Park YW: Basal cell adenoma in the parotid gland: CT and MR findings. Am J Neuroradiol 25: 631-5, 2004
Lee YH, Huang WC, Hsie MS: CTNNB1 mutations in basal cell ade- noma of the salivary gland. Journal of the Formosan Medical As- sociation 2017 https://doi.org/10.1016/j.jfma.2017.11.011
Maahs GS, Oppermann PO, Maahs LGP, Machado Filho G, Ronchi AD: Parotid gland tumors: a retrospective study of 154 patients. Braz J Otorhinolaryngol 81:301-6, 2015
Nagao T, Suqano I, Ishida Y, Matsuzaki O, Konno A, Kondo Y, Nagao K: Carcinoma in basal cell adenoma of the parotid gland. Pathol Res Pract 193(3):171–178, 1997
Rajasenthil V, Ravi A: Basal Cell Adenoma of the Parotid Gland A Rare Entity Indian J Surg 76(5):408–410, 2014
Regezzi JA Sciubba J: Salivary gland diseases. In: Regezzi and Sciubba: Oral Pathology – Clinical – Pathologic correlations. WB Saunders 1993, pp239-302
Scheller EL, Pritchett CV, Shukla A, Pepper JP, Marentette LJ, McHugh JB: Synchronous ipsilateral sebaceous lymphadenoma and mem- branous basal cell adenoma of the parotid. Oral Surg Oral Med Oral Pathol Oral Radiol. Apr;115(4):e41-6, 2013
Stathopoulos P, Igoumenakis D, Smith WP: Partial Superficial, Superfi- cial, and Total Parotidectomy in the Management of Benign Parotid Gland Tumors: A 10-Year Prospective Study of 205 Pa- tients. J Oral Maxillofac Surg. Feb;76(2):455-459, 2018
Department of Oral and Maxillofacial Surgery, General Hospital of Attica “KAT” (Head: Dr Dr G. Rallis) Department of Pathology, General Hospital of Attica “KAT” (Head: Dr Kal. Diamantopoulou)
Hellenic Archives of Oral & Maxillofacial Surgery (2018) 3, 151-157
SUMMARY: We present 3 cases of basal cell adenoma of the parotid treated at our Department. All patients complained of a retromandibular lump with clinical traits of benign parotid tumors. Diagnostic workup in all cases included tomography scans and fine needle aspiration biopsy. The former depicted parotid tumors with benign characteristics. Basal cell adenoma (BCA) was the cytology report in one of the patients, later confirmed histo- pathologically, whereas for the other two patients, FNA yielded an inconclusive report. Management included superficial parotidectomy for two cases and subtotal parotidectomy for the remaining one. All patients had an uneventful recovery. BCA is a rare benign tumor of the salivary glands. It is treated with surgical excision, similarly to more common benign tumors. A subtype of BCA, the membranous BCA, is characterized by higher recurrence rate, malignant transformation and simultaneous or later occurrence in other salivary or dermal glands. It is therefore recommended, for patients with the membranous subtype of BCA, to be long term followed up by an oral and maxillofacial surgeon, as well as a dermatologist.
KEY WORDS: basal cell adenoma, monomorphic adenoma, parotid
REFERENCES
Chiu NC, Wu HM, Chou YH, Li WY, Chiou YY, Guo WY, Chang CY: Basal Cell Adenoma Versus Pleomorphic Adenoma of the Parotid Gland: CT Findings. American Journal of Roentgenology 189 (5): 254-261, 2007
de Araujo VC: Basal cell adenoma, In: Barnes L, Everson JW, Reichart P, Sidransky D, editors: World Health Organization classification of tumors. Pathology and genetics of head and neck tumors. Lyon: IARC 2005. pp. 261-2
Fenske C, Carter N, Banerjee P, Holden C: Brooke–Spiegler Syndrome Locus Assigned to 16q12-q13. Journal of Investigative Dermatol- ogy 114(5): 1057-1058, 2000
García RG, Cha SHN, Muñoz Guerra MF, Gamallo Amat C: Basal cell adenoma of the parotid gland. Case report and review of the lit- erature. Med Oral Patol Oral Cir Bucal 11: E206-9, 2006
Gregoire C: Salivary gland tumors: the parotid gland. In: Bagheri, Bell and Khan: Current therapy in Oral and Maxillofacial Surgery, El- sevier Saunders 2012, pp 450-60
Handra-Luca A: Basal cell adenoma. Pathology Outlines.com website. http://www.pathologyoutlines.com/topic/salivaryglandsbasalcel- ladenoma.html. Accessed June 13th, 2018
Jang M, Park D, Lee SR, Hahm CK, Kim Y, Kim Y, Park CK, Tae K, Park MH, Park YW: Basal cell adenoma in the parotid gland: CT and MR findings. Am J Neuroradiol 25: 631-5, 2004
Lee YH, Huang WC, Hsie MS: CTNNB1 mutations in basal cell ade- noma of the salivary gland. Journal of the Formosan Medical As- sociation 2017 https://doi.org/10.1016/j.jfma.2017.11.011
Maahs GS, Oppermann PO, Maahs LGP, Machado Filho G, Ronchi AD: Parotid gland tumors: a retrospective study of 154 patients. Braz J Otorhinolaryngol 81:301-6, 2015
Nagao T, Suqano I, Ishida Y, Matsuzaki O, Konno A, Kondo Y, Nagao K: Carcinoma in basal cell adenoma of the parotid gland. Pathol Res Pract 193(3):171–178, 1997
Rajasenthil V, Ravi A: Basal Cell Adenoma of the Parotid Gland A Rare Entity Indian J Surg 76(5):408–410, 2014
Regezzi JA Sciubba J: Salivary gland diseases. In: Regezzi and Sciubba: Oral Pathology – Clinical – Pathologic correlations. WB Saunders 1993, pp239-302
Scheller EL, Pritchett CV, Shukla A, Pepper JP, Marentette LJ, McHugh JB: Synchronous ipsilateral sebaceous lymphadenoma and mem- branous basal cell adenoma of the parotid. Oral Surg Oral Med Oral Pathol Oral Radiol. Apr;115(4):e41-6, 2013
Stathopoulos P, Igoumenakis D, Smith WP: Partial Superficial, Superfi- cial, and Total Parotidectomy in the Management of Benign Parotid Gland Tumors: A 10-Year Prospective Study of 205 Pa- tients. J Oral Maxillofac Surg. Feb;76(2):455-459, 2018
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