Primary Leiomyosarcoma of the Mandibular Gingiva. A Case Report
Stylianos ZANAKIS, Stavros SKIADAS, Foteini IOANNIDOU
“Ippokrateio” General Hospital of Athens, Department of Oral and Maxillofacial Surgery (Acting Head: Zanakis Stylianos)
Hellenic Archives of Oral & Maxillofacial Surgery (2017) 1, 1-8
SUMMARY: Primary oral leiomyosarcomas are exceptionally rare lesions often associated with poor prognosis. We report a case of leiomyosarcoma arising in the anterior mandibular gingivae, which is a non prevalent site of ocurrence. Clinically, the tumor was far from being firm and solid as it is usually described in the literature. Light microscopy failed to confirm the true nature of the lesion on the biopsy specimen.
KEY WORDS: Leiomyosarcoma, primary, oral cavity
REFERENCES
Allen CM, Neville B, Damm DD, Marsh W: Leiomyosarcoma metasta- tic to the oral region. Report of three cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 76:752-756, 1993.
Azevedo RS, Pires FR, Gouvêa AF, Lopes MA, Jorge, J: Leiomyosarco- mas of the oral cavity: report of a radiation-associated and a metastatic case. Oral Maxillofac Surg 16: 227-232, 2011.
Dry SM, Jorgensen, JL, Fletcher CDM: Leiomyosarcomas of the oral cavity: an unusual topographic subset easily mistaken for nonmes- enchymal tumours. Histopathology 36:210-220, 2000.
Ethunandan M, Stokes C, Higgins B, Spedding A, Way C, Brennan P: Primary oral leiomyosarcoma: a clinico-pathologic study and analy- sis of prognostic factors. Int J Oral Maxillofac Surg 36: 409-416, 2007.
Farman AG, Kay S: Oral leiomyosarcoma. Report of a case and review of the literature pertaining to smooth-muscle tumors of the oral cavity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 43: 402-409, 1977.
Farole A, Manalo AE, Iranpour B: Lesion of the temporomandibular joint. J Oral Maxillofac Surg 50: 510-514, 1992.
Fernandez Sanroman J, Alonso del Hoyo JR, Diaz FJ, Gil-Diez JL, Monje F, Naval L, Alamillos FJ, Dean A, Rubio P: Sarcomas of the head and neck. Br J Oral MaxilloFac Surg 30(2): 115-118, 1992.
Fletcher CDM, Sundaram M, Rydholm A, Coindre JM, Singer S: Soft tissue tumours: Epidemiology, clinical features, histopathological typing and grading. In: World Health Organization Classification of Tumours, Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: HIARCPress, 12-18, 2002.
Hashimoto H, Daimaru Y, Tsuneyoshi M, Enjoji M: Leiomyosarcoma of the external soft tissues. A clinicopathologic, immunohisto- chemical, and electron microscopic study. Cancer 57: 2077-2088, 1986.
Izumi K, Maeda T, Cheng J, Saku T: Primary leiomyosarcoma of the maxilla with regional lymph node metastasis. Report of a case and review of the literature. Oral Surg Oral Med Oral Pathol Oral Ra- diol Endod 80: 310-319, 1995.
Kumar V, Abbas AK, Fausto N, Mitchell NR: In: Robbins Basic Pathol- ogy 8th edition, Philadelphia: PA Saunders Elsevier, 835, 2007.
Mesquita RA, Migliari DA, Sousa SOMD, Alves MR: Leiomyosarcoma of the buccal mucosa: A case report. J Oral Maxillofac Surg 56: 504-507, 1998.
Montgomery E, Goldblum JR, Fisher C: Leiomyosarcoma of the head and neck: a clinicopathological study. Histopathology 40: 518-525, 2002.
Nikitakis NG, Lopes MA, Bailey JS, Blanchaert Jr RH, Ord RA, Sauk JJ: Oral leiomyosarcoma: review of the literature and report of two cases with assessment of the prognostic and diagnostic significance of immunohistochemical and molecular markers. Oral Oncol 38: 201-208, 2002.
Nishi M, Mimura T, Senba I: Leiomyosarcoma of the maxilla. J Oral Maxillofac Surg 45:64-68, 1987.
Schenberg ME, Slootweg PJ, Koole R: Leiomyosarcomas of the oral cavity. Report of four cases and review of the literature. J Cran- iomaxillofac Surg 21:342-347, 1993.
Stout AP, Hill WT: Leiomyosarcoma of the superficial soft tissues. Can- cer 11:844-854, 1958.
Suárez-Alén F, Otero-Rey E, Peñamaría-Mallón M, García-García A, Blanco-Carrión A: Oral leiomyosarcoma: the importance of early diagnosis. Gerodontology 32(4):314-317, 2014.
Sumida T, Hamakawa H, Otsuka K, Tanioka H: Leiomyosarcoma of the maxillary sinus with cervical lymph node metastasis. J Oral Maxillofac Surg 59: 568-571, 2001.
Vilos GA, Rapidis AD, Lagogiannis GD, Apostolidis C: Leiomyosarco- mas of the Oral Tissues: Clinicopathologic Analysis of 50 Cases. J Oral Maxillofac Surg 63:1461-1477, 2005.
Weitzner S: Leiomyosarcoma of the anterior maxillary alveolar ridge. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 50(1):62-64, 1980.
Yan B, Li Y, Pan J, Xia H, Li LJ: Primary oral leiomyosarcoma: a retro- spective clinical analysis of 20 cases. Oral Dis 16:198-203, 2010.
“Ippokrateio” General Hospital of Athens, Department of Oral and Maxillofacial Surgery (Acting Head: Zanakis Stylianos)
Hellenic Archives of Oral & Maxillofacial Surgery (2017) 1, 1-8
SUMMARY: Primary oral leiomyosarcomas are exceptionally rare lesions often associated with poor prognosis. We report a case of leiomyosarcoma arising in the anterior mandibular gingivae, which is a non prevalent site of ocurrence. Clinically, the tumor was far from being firm and solid as it is usually described in the literature. Light microscopy failed to confirm the true nature of the lesion on the biopsy specimen.
KEY WORDS: Leiomyosarcoma, primary, oral cavity
REFERENCES
Allen CM, Neville B, Damm DD, Marsh W: Leiomyosarcoma metasta- tic to the oral region. Report of three cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 76:752-756, 1993.
Azevedo RS, Pires FR, Gouvêa AF, Lopes MA, Jorge, J: Leiomyosarco- mas of the oral cavity: report of a radiation-associated and a metastatic case. Oral Maxillofac Surg 16: 227-232, 2011.
Dry SM, Jorgensen, JL, Fletcher CDM: Leiomyosarcomas of the oral cavity: an unusual topographic subset easily mistaken for nonmes- enchymal tumours. Histopathology 36:210-220, 2000.
Ethunandan M, Stokes C, Higgins B, Spedding A, Way C, Brennan P: Primary oral leiomyosarcoma: a clinico-pathologic study and analy- sis of prognostic factors. Int J Oral Maxillofac Surg 36: 409-416, 2007.
Farman AG, Kay S: Oral leiomyosarcoma. Report of a case and review of the literature pertaining to smooth-muscle tumors of the oral cavity. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 43: 402-409, 1977.
Farole A, Manalo AE, Iranpour B: Lesion of the temporomandibular joint. J Oral Maxillofac Surg 50: 510-514, 1992.
Fernandez Sanroman J, Alonso del Hoyo JR, Diaz FJ, Gil-Diez JL, Monje F, Naval L, Alamillos FJ, Dean A, Rubio P: Sarcomas of the head and neck. Br J Oral MaxilloFac Surg 30(2): 115-118, 1992.
Fletcher CDM, Sundaram M, Rydholm A, Coindre JM, Singer S: Soft tissue tumours: Epidemiology, clinical features, histopathological typing and grading. In: World Health Organization Classification of Tumours, Pathology and Genetics of Tumours of Soft Tissue and Bone. Lyon: HIARCPress, 12-18, 2002.
Hashimoto H, Daimaru Y, Tsuneyoshi M, Enjoji M: Leiomyosarcoma of the external soft tissues. A clinicopathologic, immunohisto- chemical, and electron microscopic study. Cancer 57: 2077-2088, 1986.
Izumi K, Maeda T, Cheng J, Saku T: Primary leiomyosarcoma of the maxilla with regional lymph node metastasis. Report of a case and review of the literature. Oral Surg Oral Med Oral Pathol Oral Ra- diol Endod 80: 310-319, 1995.
Kumar V, Abbas AK, Fausto N, Mitchell NR: In: Robbins Basic Pathol- ogy 8th edition, Philadelphia: PA Saunders Elsevier, 835, 2007.
Mesquita RA, Migliari DA, Sousa SOMD, Alves MR: Leiomyosarcoma of the buccal mucosa: A case report. J Oral Maxillofac Surg 56: 504-507, 1998.
Montgomery E, Goldblum JR, Fisher C: Leiomyosarcoma of the head and neck: a clinicopathological study. Histopathology 40: 518-525, 2002.
Nikitakis NG, Lopes MA, Bailey JS, Blanchaert Jr RH, Ord RA, Sauk JJ: Oral leiomyosarcoma: review of the literature and report of two cases with assessment of the prognostic and diagnostic significance of immunohistochemical and molecular markers. Oral Oncol 38: 201-208, 2002.
Nishi M, Mimura T, Senba I: Leiomyosarcoma of the maxilla. J Oral Maxillofac Surg 45:64-68, 1987.
Schenberg ME, Slootweg PJ, Koole R: Leiomyosarcomas of the oral cavity. Report of four cases and review of the literature. J Cran- iomaxillofac Surg 21:342-347, 1993.
Stout AP, Hill WT: Leiomyosarcoma of the superficial soft tissues. Can- cer 11:844-854, 1958.
Suárez-Alén F, Otero-Rey E, Peñamaría-Mallón M, García-García A, Blanco-Carrión A: Oral leiomyosarcoma: the importance of early diagnosis. Gerodontology 32(4):314-317, 2014.
Sumida T, Hamakawa H, Otsuka K, Tanioka H: Leiomyosarcoma of the maxillary sinus with cervical lymph node metastasis. J Oral Maxillofac Surg 59: 568-571, 2001.
Vilos GA, Rapidis AD, Lagogiannis GD, Apostolidis C: Leiomyosarco- mas of the Oral Tissues: Clinicopathologic Analysis of 50 Cases. J Oral Maxillofac Surg 63:1461-1477, 2005.
Weitzner S: Leiomyosarcoma of the anterior maxillary alveolar ridge. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 50(1):62-64, 1980.
Yan B, Li Y, Pan J, Xia H, Li LJ: Primary oral leiomyosarcoma: a retro- spective clinical analysis of 20 cases. Oral Dis 16:198-203, 2010.
How to cite this article:
|
View the full-text PDF:
|
| ||