SOLITARY FIBROUS TUMOR OF THE HEAD AND NECK COMPARTMENT, OUR EXPERIENCE IN TREATMENT AND FOLLOW UP
Authors:
Dr. F. Galvano, Prof. A. Cassoni, Dr. G. Scivoletto, Dr. D. Di Carlo, Dr. R. Pucci, Dr. M. Della Monaca, Prof. V. Valentini
Affiliation:
University of Rome “La Sapienza”, residency program in maxillofacial surgery
Doi: 10.54936/haoms242p73
ABSTRACT:
Solitary fibrous tumor (SFT) comprises a histologic spectrum of lrarely metastasizing fibroblastic mesenchymal neoplasms that includes tumors formerly classified as hemangiopericytoma , it most frequently arises in the intra thoracic region but are now known to occur at any site, including the head and neck, in approximately 20% of cases. Clinical presentation in the head and neck varies by anatomic location and compressive symptoms due to indolent growth.
The STF has no gender predilection, and is mostly described as an asymtomatic growing mass in middle-aged adults, when talking about its extrathoracic counterpart though, literature describes a slight more frequent insurgence in women than men. In its extrapleural representation, symptoms are mainly aspecific, due to the presence of a growing mass.
Histologically, this tumor is composed of short spindle/polygonal cells that grow in what has been described as a “patternless” growth pattern, alternating hyper cellular and hypo cellular sclerotic foci, keloid like stromal hyalinization and prominent “staghorn”vascular branching.
The most frequent behavior of this tumor is benign and follows an indolent course, although it has a 20% of malignancy, often defined by markedly increased cellularity and/or the presence of ≥4 mitoses per 10 high- power fields (hpf).
Because of its benign appearance, the treatment of choice for STF in surgical excision in wide free margins. Sometimes though, recurrence and metastasis are possible. Studies show an association between lesion size, increased mitosis, increased cellularity, hemorrhage and necrosis, and clinical behavior.
In our study we describe our experience in the treatment of solitary fibrous tumor of the head and neck compartment on a series of 13 patients.
KEY WORDS:
Authors:
Dr. F. Galvano, Prof. A. Cassoni, Dr. G. Scivoletto, Dr. D. Di Carlo, Dr. R. Pucci, Dr. M. Della Monaca, Prof. V. Valentini
Affiliation:
University of Rome “La Sapienza”, residency program in maxillofacial surgery
Doi: 10.54936/haoms242p73
ABSTRACT:
Solitary fibrous tumor (SFT) comprises a histologic spectrum of lrarely metastasizing fibroblastic mesenchymal neoplasms that includes tumors formerly classified as hemangiopericytoma , it most frequently arises in the intra thoracic region but are now known to occur at any site, including the head and neck, in approximately 20% of cases. Clinical presentation in the head and neck varies by anatomic location and compressive symptoms due to indolent growth.
The STF has no gender predilection, and is mostly described as an asymtomatic growing mass in middle-aged adults, when talking about its extrathoracic counterpart though, literature describes a slight more frequent insurgence in women than men. In its extrapleural representation, symptoms are mainly aspecific, due to the presence of a growing mass.
Histologically, this tumor is composed of short spindle/polygonal cells that grow in what has been described as a “patternless” growth pattern, alternating hyper cellular and hypo cellular sclerotic foci, keloid like stromal hyalinization and prominent “staghorn”vascular branching.
The most frequent behavior of this tumor is benign and follows an indolent course, although it has a 20% of malignancy, often defined by markedly increased cellularity and/or the presence of ≥4 mitoses per 10 high- power fields (hpf).
Because of its benign appearance, the treatment of choice for STF in surgical excision in wide free margins. Sometimes though, recurrence and metastasis are possible. Studies show an association between lesion size, increased mitosis, increased cellularity, hemorrhage and necrosis, and clinical behavior.
In our study we describe our experience in the treatment of solitary fibrous tumor of the head and neck compartment on a series of 13 patients.
KEY WORDS: