UP, UP, AND AWAY; HOW PANTON-VALENTINE LEUKOCIDIN STAPHYLOCOCCUS AUREUS INFECTION GROUNDED A FLIGHT ATTENDANT
Authors:
Fletcher and Cook
Affiliation:
Doi: 10.54936/haoms242p34
ABSTRACT:
Objectives: To highlight Panton-Valetine Leukocidin positive Staphylococcus Aureus (PVL-SA) as a potential source of infection in severe/ recurrent skin infections in fit and healthy individuals. To highlight at risk groups. To demonstrate relevant microbiological investigations. To emphasise the importance of prompt surgical management in PVL-SA cases. To highlight the geographical spread of PVL-SA strains.
Materials and methods: Presenting a case of a severe PVL-SA upper lip infection. Using the case to highlight key learning points for management of PVL-SA patients. A pictorial and descriptive illustration of a patient’s journey from emergency referral, admission, surgery, antimicrobial management and follow up in an Oral and Maxillofacial Surgery unit. Using sequential pictures, haematological and biochemical results to demonstrate the patient’s clinical progress. Discussing the patient’s microbiology results over time and testing pathways for PVL, its limitations, and benefits.
Results: This patient had PVL positive Methicillin-Sensitive Staphylococcus Aureus (MSSA) rather than Methicillin-Resistant Staphylococcus Aureus (MRSA). The patient made a full recovery following prompt surgical intervention and appropriate antibiotic use. The patients General Practitioner provided appropriate follow-up infection prevention measures.
Conclusion: PVL-SA MSSA subtype is most common in Europe, compared to North America where the MRSA subtype is more prevalent and attributable to the USA300 strain. The Centre for Disease Control and Prevention have outlined 5 C’s (Contaminated items, Close contact, Crowding, Cleanliness, Cuts and other Compromised skin infections) as risk factors for PVL-SA. MSSA skin infections where prompt surgical management is provided can significantly reduce the length of stay in hospital. Liaison with microbiology following PVL results may guide antimicrobial selection especially in deep invasive PVL-SA infections for example in children, pneumonias and osteomyelitis cases. PVL-SA skin infections are associated with better prognoses. Clinicians managing severe/recurrent infections should be suspicious of PVL positive staphylococcus aureus as a source of infection- especially in at risk groups and healthy individual.
KEY WORDS: Panton-Valentine Leukocidin positive Staphylococcus Aureus
Authors:
Fletcher and Cook
Affiliation:
Doi: 10.54936/haoms242p34
ABSTRACT:
Objectives: To highlight Panton-Valetine Leukocidin positive Staphylococcus Aureus (PVL-SA) as a potential source of infection in severe/ recurrent skin infections in fit and healthy individuals. To highlight at risk groups. To demonstrate relevant microbiological investigations. To emphasise the importance of prompt surgical management in PVL-SA cases. To highlight the geographical spread of PVL-SA strains.
Materials and methods: Presenting a case of a severe PVL-SA upper lip infection. Using the case to highlight key learning points for management of PVL-SA patients. A pictorial and descriptive illustration of a patient’s journey from emergency referral, admission, surgery, antimicrobial management and follow up in an Oral and Maxillofacial Surgery unit. Using sequential pictures, haematological and biochemical results to demonstrate the patient’s clinical progress. Discussing the patient’s microbiology results over time and testing pathways for PVL, its limitations, and benefits.
Results: This patient had PVL positive Methicillin-Sensitive Staphylococcus Aureus (MSSA) rather than Methicillin-Resistant Staphylococcus Aureus (MRSA). The patient made a full recovery following prompt surgical intervention and appropriate antibiotic use. The patients General Practitioner provided appropriate follow-up infection prevention measures.
Conclusion: PVL-SA MSSA subtype is most common in Europe, compared to North America where the MRSA subtype is more prevalent and attributable to the USA300 strain. The Centre for Disease Control and Prevention have outlined 5 C’s (Contaminated items, Close contact, Crowding, Cleanliness, Cuts and other Compromised skin infections) as risk factors for PVL-SA. MSSA skin infections where prompt surgical management is provided can significantly reduce the length of stay in hospital. Liaison with microbiology following PVL results may guide antimicrobial selection especially in deep invasive PVL-SA infections for example in children, pneumonias and osteomyelitis cases. PVL-SA skin infections are associated with better prognoses. Clinicians managing severe/recurrent infections should be suspicious of PVL positive staphylococcus aureus as a source of infection- especially in at risk groups and healthy individual.
KEY WORDS: Panton-Valentine Leukocidin positive Staphylococcus Aureus