Non-Hodgkin’s lymphoma of the maxilla mimicking a dentoalveolar abscess.
Case report
Ioannis MELAKOPOULOS, Haralambos GKILAS, Sofia MELLOU, Konstantinos TOSIOS
OMFS Clinic of Private Hospital Mediterraneo, Pathological Oncology Dept. “G. Genimatas” Hospital, Oral Pathology Clinic of Dental School of Athens, Greece
Hellenic Archives of Oral & Maxillofacial Surgery (2012) 2, 93-98
SUMMARY: Lymphomas, although rare, constitute the third most common malignancy of the oral cavity, following squamous cell carcinoma and salivary gland adenocarcinomas. Most oral lymphomas are Non-Hodgkin and derive from B-lymphocytes. They usually appear as soft tissue masses of the palate or gingiva. Sometimes they mimic common oral diseases such as inflammatory or reactive lesions and therefore pose a challenge to proper and timely diagnosis. A case of a follicular Non-Hodgkin’s lymphoma, appe - aring as a swelling of the maxilla, initially considered to be of inflammatory/infectious cause is presented. The patient had already undergone antibiotic therapy and extraction of the adjacent tooth without resolution of the lesion, at the time an incisional biopsy was decided. The clinician needs to always maintain a high index of suspicion when coming across diffuse swellings that despite the fact that they resemble common pathoses, do not respond to conventional therapy or appear unusual in some way.
KEY WORDS: follicular Non-Hodgkin lymphoma, dentoalveolar abscess
REFERENCES
Ardekian L, Peleg M, Samet N, Givol N, Taicher S: Burkitt's lymphoma mimicking an acute dentoalveolar abscess. J Endod 22:697-8, 1996
Barker GR: Unifocal lymphomas of the oral cavity. Br J Oral Maxillofac Surg 22:426-30, 1984
Bavitz JB, Patterson DW, Sorensen S: Non-Hodgkin's lymphoma disguised as odontogenic pain. J Am Dent Assoc 123:99-100, 1992
Ekstrom-Smedby K: Epidemiology and etiology of non-Hodgkin lymphoma--a review. Acta Oncol 45:258-71, 2006
Engels EA: Infectious agents as causes of non-Hodgkin lymphoma. Cancer Epidemiol Biomarkers Prev 16:401-4, 2007
Epstein JB, Epstein JD, Le ND, Gorsky M: Characteristics of oral and paraoral malignant lymphoma: a population-based review of 361 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 92:519-25, 2001
Etemad-Moghadam S, Tirgary F, Keshavarz S, Alaeddini M: Head and neck non-Hodgkin's lymphoma: a 20-year demographic study of 381 cases. Int J Oral Maxillofac Surg 39:869-72, 2010
Graham RM, Thomson EF, Cousin GC, Kumar SN, Awasthi A: A case of facial lymphoma mimicking dental infection. Dent Update 36:244-6, 2009
Hayashi D, Lee JC, Devenney-Cakir B, Zaim S, Ounadjela S, SolalCeligny P et al.: Follicular non-Hodgkin's lymphoma. Clin Radiol 65:408-20, 2010 Karlis V, Glickman RS, Isdith K, Jones JL: Right facial edema associated with localized gingival swelling. J Oral Maxillofac Surg 56:760-4, 1998
Kemp S, Gallagher G, Kabani S, Noonan V, O'Hara C: Oral nonHodgkin's lymphoma: review of the literature and World Health Organization classification with reference to 40 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105:194-201, 2008
Keyes GG, Balaban FS, Lattanzi DA: Periradicular lymphoma: differentiation from inflammation. Oral Surg Oral Med Oral Pathol 66:230-5, 1998
Kolokotronis A, Konstantinou N, Christakis I, Papadimitriou P, Matia - kis A, Zaraboukas T et al.: Localized B-cell non-Hodgkin's lymphoma of oral cavity and maxillofacial region: a clinical study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 99:303-10, 2005
Martinelli-Klay CP, Martinelli CR, Martinelli C, Dias JB, Cheade TC, Lombardi T: Primary extranodal non-Hodgkin lymphoma of the gingiva initially misdiagnosed as dental abscess. Quintessence Int 40:805-8, 2009
Mawardi H, Cutler C, Treister N: Medical management update: NonHodgkin lymphoma. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 107:e19-33, 2009 Maxymiw WG, Goldstein M, Wood RE: Extranodal non-Hodgkin's lymphoma of the maxillofacial region: analysis of 88 consecutive cases. SADJ 56:524-7, 2001
Mealey BL, Tunder GS, Pemble CW 3rd: Primary extranodal malignant lymphoma affecting the periodontium. J Periodontol 73:937-41, 2002
Payne M, al-Damouk JD: Gingival swelling as a manifestation of nonHodgkin's lymphoma. Br Dent J 175:293-4, 1993
Richards A, Costelloe MA, Eveson JW, Scully C, Irvine GH, Rooney N: Oral mucosal non-Hodgkin's lymphoma--a dangerous mimic. Oral Oncol 36:556-8, 2000 Rinaggio J, Aguirre A, Zeid M, Hatton MN: Swelling of the nasolabial area. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 89:669-73, 2000
Rog RP: Beware of malignant lymphoma masquerading as facial inflam - matory processes. Oral Surg Oral Med Oral Pathol 71:415-9, 1991
Saund D, Kotecha S, Rout J, Dietrich T: Non-resolving periapical inflammation: a malignant deception. Int Endod J 43:84-90, 2010
Spatafore CM, Keyes G, Skidmore AE: Lymphoma: an unusual oral presentation. J Endod 15:438-41, 1989
The Non-Hodgkin's Lymphoma Classification Project: A clinical evaluation of the Inte rnational Lymphoma Study Group classification of non-Hodgkin's lymphoma, Blood 89:3909-18, 1997
Triantafillidou K, Dimitrakopoulos J, Iordanidis F, Gkagkalis A: Extra - nodal Non-Hodgkin Lymphomas of the Oral Cavity and Ma - xillofacial Region: A Clinical Study of 58 Cases and Review of the Literature. J Oral Maxillofac Surg 2012
van der Waal RI, Huijgens PC, van der Valk P, van der Waal I: Chara - cteristics of 40 primary extranodal non-Hodgkin lymphomas of the oral cavity in perspective of the new WHO classification and the International Prognostic Index. Int J Oral Maxillofac Surg 34:391-5, 2005
Vega F, Lin P, Medeiros LJ: Extranodal lymphomas of the head and neck. Ann Diagn Pathol 9:340-50, 2005
Vitolo U, Ferreri AJ, Montoto S: Follicular lymphomas. Crit Rev Oncol Hematol 66:248-61, 2008
Wright JM, Radman WP: Intrabony lymphoma simulating periradicular inflammatory disease. J Am Dent Assoc 126:101-5, 1995erial. Stoma 36(4): 291-303, 2008
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