Immunohistochemical evaluation of transforming growth factor (TGF-b1) in
malignant salivary gland tumours
Panagiotis TZOUTZOUKOS, Kety NICOPOULOU-KARAYIANNI, Aikaterini DONTA-BAKOGIANNI
Clinic of Oral Diagnosis and Radiology , Dental School, University of Athens (Head: Professor K. Tsiklakis)
Hellenic Archives of Oral & Maxillofacial Surgery (2011) 3, 165-178
SUMMARY: Objectives: (1) To compare the diagnostic validity of a 2nd and a 1st generation DSR system in the detection of periodontal bone changes (2) to compare the shape and size of corresponding alveolar bone changes in the subtraction images from the two DSR systems. Methods: Periodontal lesions of varying sizes were created on a human dry skull. Standardized and non-standardized radiographs were acquired and subtracted with a 1st and a 2nd generation DSR system. Six oral radiologists evaluated the subtraction images. Results: The differences in all values of diagnostic accuracy between the two generations DSR systems were found to be statistically significant. No difference in the sensitivity of the two DSR systems was found when the largest lesions (1.6 mm) were studied. Median values for differences in shape and size were 1 and |1.5| re - spectively. The correlation coefficient (r) between the differences in the two parameters was 0.84. Conclusions: The 2nd generation DSR system has shown to have a satisfactory diagnostic accuracy only when bone changes of at least 1.6 mm in diameter are studied.
KEY WORDS: digital subtraction radiography; image registration; periodontal bone changes
REFERENCES
Allen KM, Hausmann E, Kutlubay ME, Loza J, Carpio LC, Ortman et al.: Studies of the angular reproducibility of positioning patients adjacent to an x-ray tube:1. Stent-rod based and extraoral systems. J Periodont Res 29:174-178, 1994
Bittar-Cortez JA, Passeri LA, de Almeida SM, Haiter-Neto F: Compa - rison of peri-implant bone level assessment in digitized conventional radiographs and digital subtraction images. Dentomaxillo - facial Radiology 35:258-262, 2006
Byrd V, Mayfield-Donahoo T, Reddy MS, Jeffcoat MK: Semiauto - mated image registration for digital subtraction radiography. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 85:473-478, 1998
Davis M, Allen KM, Hausmann E: Effects of small angle discrepancies on interpretations of subtraction images. Oral Surg Oral Med Oral Pathol 78:397-400, 1994
Dove BS, McDavid DW, Hamilton KE: Analysis of sensitivity and specificity of a new digital subtraction system. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 89:771-6, 2000
Dunn SM, van der Stelt PF: Recognizing invariant geometric structure in dental radiographs. Dentomaxillofac Radiol 21:142-147, 1992
Dunn SM, van der Stelt PF, Ponce A, Fenesy K, Shah S: A comparison of two registration techniques for digital subtraction radiography. Dentomaxillofac Radiol 22:77-80, 1993
Eickholz P, Hausmann E: Accuracy of radiographic assessment of interproximal bone loss in intrabony defects using linear measurements. Eur J Oral Sci 108:70-73, 2000
Ellwood RP, Davies RM, Worthington HV: Evaluation of a dental subtraction radiography system. J Periodont Res 32:241-248, 1997
Ettinger GJ, Gordon GG, Goodson JM, Socransky SS, Williams R: Development of automated registration algorithms for subtraction radiography. J Clin Periodontol 21:540-543, 1994
Fidler A, Likar B, Pernus F, Skaleric U: Influence of developer exhaustion on accuracy of quantitative digital subtraction radiography: an in vitro study. Oral Surgery Oral Medicine Oral Patho logy Oral Radiology & Endodontics 90:233-239, 2000
Groendahl HG, Groendahl K, Webber R: A digital subtraction technique for dental radiography. Oral Surg Oral Med Oral Pathol. Jan 55(1):96-102, 1983 Gröndahl HG, Gröndahl K and Webber RL: Influence of variation in projection geometry on the detectibility of periodontal bone lesions. J Clin Periodontol 11:411-420, 1984 Haiter-Neto F, Ferreira RI, Tabchoury CPM and Boscolo FN: Linear and Logarithmic subtraction for detecting enamel subsurface de - mineralization. Dentomaxillofacial Radiology 34:133-139, 2005
Huh KH, Lee SS, Jeon IS, Yi WJ, Heo MS, Choi SC: Quantative analysis of errors in alveolar crest level caused by discrepant projection geometry in digital subtraction radiography: an in vivo study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 100:750- 755, 2005
Lehmann TM, Gröndahl K, Gröndahl HG, Schmidt W and Spitzer K: Observer – independent registration of perspective projection prior to subtraction of in vivo radiographs. Dentomaxillofac Radiol 27:140-150, 1998 Lehmann TM, Gröndahl HG, Benn DK: Computer-based registration for digital subtraction in dental radiology. Dentomaxillofac Radiol 29:323-346, 2000
Likar B, Pernus F: Automatic extraction of corresponding points for the registration of medical images. Med Phys 26:1678-1686, 1999
Mol A, Dunn SM: The performance of projective standardization for digital subtraction radiography. Oral Surg Oral Med Oral PatholOral Radiol Endod 2003;96:373-382, 2003
Nicopoulou-Karayianni K, Braegger U, Patrikiou A, Stassinakis A, Lang NP. Image processing for enhanced observer agreement in the evaluation of periapical bone changes. Int Endod J 35:615-722, 2002
Οhki M, Okano T and Yamada N: A contrast-correction method for digital subtraction radiography. J Period Res 23:277-280, 1988
Ono E, Filho EM, Leite HF, Tanaka JLO, De Moraes MEL, De Melo Castilho JC: Evaluation of simulated external root resorptions with digital radiography and digital subtraction radiography. Am J Orthod Dentofacial Orthop: 139:324-333, 2011
Ostuni J, Fisher D, van der Stelt PF, Dunn SM: Registration of dental radiographs using projective geometry. Dentomaxillofac Radiol 22:199-203, 1993
Parsell DE, Gatewood RS, Watts JD, Streckfus CF: Sensitivity of va rious radiographic methods for detection of oral cancellous bone lesions. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 86:498-502, 1998
Potter BJ, Shrout MK, Harrell JC: Reproducibility of beam alignment using different bite-wing radiographic techniques. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 79:532-53, 1995
Reukers E, Sanderink G, Kuijpers-Jagtman AM, van’t Hof M: Assessment of apical root resorption using digital reconstruction. Dentomaxillofac Radiol 27:25-29, 1998
Rudolph DJ, White SC: Film-holding instruments for intraoral subtraction radiography. Oral Surg Oral Med Oral Pathol 65:767- 762, 1988
Rüttimann UE, Webber RL, Schmidt E: A robust digital method for film contrast correction in subtraction radiography. J Periodont Res 21:486-495, 1986 Versteeg KH and Van der Stelt PF: Effect of logarithmic contrast enhancement on subtraction images. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 80:479-486, 1995
Zacharaki EI, Matsopoulos GK, Asvestas PA, Nikita KS, Gröndahl K, Gröndahl HG: A digital subtraction radiography scheme based on automatic multiresolutional registration. Dentomaxillofac Radiol 33:379-390, 2004
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