TRIPLE-FAT GRAFTING TECHNIQUE: A MULTILAYER APPROACH TO FACIAL CUTANEOUS SCLEROSIS
Authors:
Antonio Arena
Affiliation:
University of Naples Federico II, Naples, Italy
Doi: 10.54936/haoms242p57
ABSTRACT:
Objectives: Systemic sclerosis (SSc) is a heterogeneous, chronic connective tissue disease, characterized by skin fibrosis, vascular and visceral lesions. Two subtypes with cutaneous involvement have been described: limited and diffuse cutaneous disease. In both of them the face is frequently affected, with related aesthetic and functional disorders. The aim of our study is to propose an innovative protocol for the treatment of skin sclerosis based on the simultaneous use of autologous fat grafts processed with three different methods: Macrofat, Microfat and Nanofat.
Materials and Methods: The study design was based on a technical note as the following protocol: The procedure was performed under general anesthesia and the donor site was the abdomen. Three different modality to process the harvested fat were performed:Macrofat was used to restore the volume of the lip and perioral rim and zygomatic area injecting with a 18 gauge cannula. Microfat was placed to improve the nasolabial folds and the cheeckbone area through a 20 gauge cannula. Nanofat was injected superficially in the perioral wrinkles and in the vermilion border using a 27 gauge needle.
Results: Macrofat was infiltrated for its volumizing effect. Microfat has been exploited for its regenerative and filling action and the biorevitalizing effect of nanofat improved perioral wrinkles and the motility of the lips increasing the mouth opening. The high number of mesenchymal stem cells (ASCs) obtained with this technique represent the major advantage compared to any other body tissue graft. The limit of the procedure is represented by the survival time of the grafted fat, due to the reabsorption of the adipose tissue.
Conclusion: In conclusion this surgical technique resulted in a greater elasticity of the skin tissue, a smoothing of the perioral wrinkles with an improvement in microstomy, drooling and fatigue. To achieve the ideal volume, repeated injections are indicated.
KEY WORDS: Systemic sclerosis, Facial Sclerosis, Lipofilling, Fat graft, Microfat, Nanofat
Authors:
Antonio Arena
Affiliation:
University of Naples Federico II, Naples, Italy
Doi: 10.54936/haoms242p57
ABSTRACT:
Objectives: Systemic sclerosis (SSc) is a heterogeneous, chronic connective tissue disease, characterized by skin fibrosis, vascular and visceral lesions. Two subtypes with cutaneous involvement have been described: limited and diffuse cutaneous disease. In both of them the face is frequently affected, with related aesthetic and functional disorders. The aim of our study is to propose an innovative protocol for the treatment of skin sclerosis based on the simultaneous use of autologous fat grafts processed with three different methods: Macrofat, Microfat and Nanofat.
Materials and Methods: The study design was based on a technical note as the following protocol: The procedure was performed under general anesthesia and the donor site was the abdomen. Three different modality to process the harvested fat were performed:Macrofat was used to restore the volume of the lip and perioral rim and zygomatic area injecting with a 18 gauge cannula. Microfat was placed to improve the nasolabial folds and the cheeckbone area through a 20 gauge cannula. Nanofat was injected superficially in the perioral wrinkles and in the vermilion border using a 27 gauge needle.
Results: Macrofat was infiltrated for its volumizing effect. Microfat has been exploited for its regenerative and filling action and the biorevitalizing effect of nanofat improved perioral wrinkles and the motility of the lips increasing the mouth opening. The high number of mesenchymal stem cells (ASCs) obtained with this technique represent the major advantage compared to any other body tissue graft. The limit of the procedure is represented by the survival time of the grafted fat, due to the reabsorption of the adipose tissue.
Conclusion: In conclusion this surgical technique resulted in a greater elasticity of the skin tissue, a smoothing of the perioral wrinkles with an improvement in microstomy, drooling and fatigue. To achieve the ideal volume, repeated injections are indicated.
KEY WORDS: Systemic sclerosis, Facial Sclerosis, Lipofilling, Fat graft, Microfat, Nanofat