Mucormycosis. Case report and literature review
Shunmugavelu KARTHIK1, Arasu SHANMUGAM2, Evangeline Cynthia DHINAKARAN3, Shenbagasavari Perumal JANANI4, Raghavelu Narendran MUGUNDAN5
1,3,4,5 Dentistry/Oral and Maxillofacial Pathology, Mercy Multispeciality Dental Centre, Chrompet, Chennai, Tamilnadu, India
2 Oral and maxillofacial surgery, Fortis Hospital, Vadapalani, Chennai, Tamilnadu, India
Hellenic Archives of Oral & Maxillofacial Surgery (2021) 1, 37-41
DOI https://dx.doi.org/10.54936/haoms2213741
SUMMARY: Mucormycosis the life-threatening opportunistic fungal infection affects primarily immuno-compromised patients in an aggressive manner. Mucormycosis in the oral cavity is not common. The case we report presented with infra orbital swelling and pain with radiographic appearance of small area of bone destruction in maxillary anterior region. The patient also had uncontrolled type 2 diabetes. The patient underwent extraction of his anterior teeth 10 days back before he developed the swelling and pain. The primary diagnosis was osteomyelitis. After the histopathology diagnosis of mucormycosis the patient was immediately started with Amphotericin-b and surgical debridement of the involved site was done. The combination of medical and surgical treatment of mucormycosis will have good prognosis.
KEY WORDS: mucormycosis, amphotericin-b, type 2 diabetes, surgical debridement.
REFERENCES
Reid G, Lynch III JP, Fishbein MC, Clark NM. Mucormycosis. InSeminars in respiratory and critical care medicine 2020 Feb (Vol. 41, No. 01, pp. 099-114). Thieme Medical Publishers.
Kancharu FK, Viswam V, Sreeram P, Warrier A, Karunakaran A. Mucormycosis of Neck a Rare Presentation. Indian Journal of Oto- laryngology and Head & Neck Surgery. 2020 Aug 5:1-5.
Prabhu RM, Patel R. Mucormycosis and entomophthoramycosis: a review of the clinical manifestations, diagnosis and treatment. Clinical Microbiology and Infection. 2004 Mar;10:31-47.
Palacios JJ, Hanson EV, Rendon MA, Infante RS. Reconstruction of Head and Neck Mucormycosis: A Literature Review and Own Experience in Immediate Reconstruction. Journal of Reconstruc- tive Microsurgery Open. 2019 Jul;4(02):e65-72.
Epstein JB, Kupferman SB, Zabner R, Rejali A, Hopp ML, Lill M, Tzach- anis D. Early diagnosis and successful management of oral mu- cormycosis in a hematopoietic stem cell transplant recipient: case report and literature review. Supportive Care in Cancer. 2016 Aug 1;24(8):3343-6.\
Bakathir AA. Mucormycosis of the jaw after dental extractions: two case reports. Sultan Qaboos University Medical Journal. 2006 Dec;6(2):77.
Rani SU, Sivaranjani Y, Kumar MP, Rao GV. Rhinocerebral mucormycosis associated with actinomycosis in a diabetic patient: A rare presentation. Journal of Oral and Maxillofacial Pathology: JOMFP. 2019 Feb;23(Suppl 1):122.
Nicolatou-Galitis O, Sachanas S, Drogari-Apiranthitou M, Moschogiannis M, Galiti D, Yiakoumis X, Rontogianni D, Yiotakis I, Petrikkos G, Pangalis G. Mucormycosis presenting with dental pain and palatal ulcer in a patient with chronic myelomonocytic leukaemia: case report and literature review. JMM Case Reports. 2015 Feb 1;2(1):e000014.
Cheong HS, Kim SY, Ki HK, Kim JY, Lee MH. Oral mucormycosis in patients with haematologic malignancies in a bone marrow trans- plant unit. Mycoses. 2017 Dec;60(12):836-41.
Cohen A, Shoukair FL, Korem M, Shaulov A, Casap N. Successful Mandibular Mucormycosis Treatment in the Severely Neutropenic Patient. Journal of Oral and Maxillofacial Surgery. 2019 Jun 1;77(6):1209-e1.
Shastry S, Murthy P, Jyotsna T, Kumar N. Cone beam computed to- mography: A diagnostic aid in rhinomaxillary mucormycosis following tooth extraction in patient with diabetes mellitus. Journal of Indian Academy of Oral Medicine and Radiology. 2020;32(1):60-4.
Rai S, Misra D, Misra A, Jain A, Jain P, Dhawan A. Palatal mucormycosis masquerading as bacterial and fungal osteomyelitis: A rare case report. Contemporary clinical dentistry. 2018 Apr;9(2):309.
Kudo K, Hasegawa H, Sato E, Kaneko T, Ishida D, Kanno C, Endo M. A case of rhinocerebral mucormycosis extending into the skull. Journal of oral and maxillofacial surgery, medicine, and pathology. 2017 Jan 1;29(1):61-4.
Swain SK, Behera IC, Mohanty JN. Mucormycosis in head-and-neck region–Our experiences at a tertiary care teaching hospital of East- ern India. Annals of Indian Academy of Otorhinolaryngology Head and Neck Surgery. 2019 Jul 1;3(2):58.
1,3,4,5 Dentistry/Oral and Maxillofacial Pathology, Mercy Multispeciality Dental Centre, Chrompet, Chennai, Tamilnadu, India
2 Oral and maxillofacial surgery, Fortis Hospital, Vadapalani, Chennai, Tamilnadu, India
Hellenic Archives of Oral & Maxillofacial Surgery (2021) 1, 37-41
DOI https://dx.doi.org/10.54936/haoms2213741
SUMMARY: Mucormycosis the life-threatening opportunistic fungal infection affects primarily immuno-compromised patients in an aggressive manner. Mucormycosis in the oral cavity is not common. The case we report presented with infra orbital swelling and pain with radiographic appearance of small area of bone destruction in maxillary anterior region. The patient also had uncontrolled type 2 diabetes. The patient underwent extraction of his anterior teeth 10 days back before he developed the swelling and pain. The primary diagnosis was osteomyelitis. After the histopathology diagnosis of mucormycosis the patient was immediately started with Amphotericin-b and surgical debridement of the involved site was done. The combination of medical and surgical treatment of mucormycosis will have good prognosis.
KEY WORDS: mucormycosis, amphotericin-b, type 2 diabetes, surgical debridement.
REFERENCES
Reid G, Lynch III JP, Fishbein MC, Clark NM. Mucormycosis. InSeminars in respiratory and critical care medicine 2020 Feb (Vol. 41, No. 01, pp. 099-114). Thieme Medical Publishers.
Kancharu FK, Viswam V, Sreeram P, Warrier A, Karunakaran A. Mucormycosis of Neck a Rare Presentation. Indian Journal of Oto- laryngology and Head & Neck Surgery. 2020 Aug 5:1-5.
Prabhu RM, Patel R. Mucormycosis and entomophthoramycosis: a review of the clinical manifestations, diagnosis and treatment. Clinical Microbiology and Infection. 2004 Mar;10:31-47.
Palacios JJ, Hanson EV, Rendon MA, Infante RS. Reconstruction of Head and Neck Mucormycosis: A Literature Review and Own Experience in Immediate Reconstruction. Journal of Reconstruc- tive Microsurgery Open. 2019 Jul;4(02):e65-72.
Epstein JB, Kupferman SB, Zabner R, Rejali A, Hopp ML, Lill M, Tzach- anis D. Early diagnosis and successful management of oral mu- cormycosis in a hematopoietic stem cell transplant recipient: case report and literature review. Supportive Care in Cancer. 2016 Aug 1;24(8):3343-6.\
Bakathir AA. Mucormycosis of the jaw after dental extractions: two case reports. Sultan Qaboos University Medical Journal. 2006 Dec;6(2):77.
Rani SU, Sivaranjani Y, Kumar MP, Rao GV. Rhinocerebral mucormycosis associated with actinomycosis in a diabetic patient: A rare presentation. Journal of Oral and Maxillofacial Pathology: JOMFP. 2019 Feb;23(Suppl 1):122.
Nicolatou-Galitis O, Sachanas S, Drogari-Apiranthitou M, Moschogiannis M, Galiti D, Yiakoumis X, Rontogianni D, Yiotakis I, Petrikkos G, Pangalis G. Mucormycosis presenting with dental pain and palatal ulcer in a patient with chronic myelomonocytic leukaemia: case report and literature review. JMM Case Reports. 2015 Feb 1;2(1):e000014.
Cheong HS, Kim SY, Ki HK, Kim JY, Lee MH. Oral mucormycosis in patients with haematologic malignancies in a bone marrow trans- plant unit. Mycoses. 2017 Dec;60(12):836-41.
Cohen A, Shoukair FL, Korem M, Shaulov A, Casap N. Successful Mandibular Mucormycosis Treatment in the Severely Neutropenic Patient. Journal of Oral and Maxillofacial Surgery. 2019 Jun 1;77(6):1209-e1.
Shastry S, Murthy P, Jyotsna T, Kumar N. Cone beam computed to- mography: A diagnostic aid in rhinomaxillary mucormycosis following tooth extraction in patient with diabetes mellitus. Journal of Indian Academy of Oral Medicine and Radiology. 2020;32(1):60-4.
Rai S, Misra D, Misra A, Jain A, Jain P, Dhawan A. Palatal mucormycosis masquerading as bacterial and fungal osteomyelitis: A rare case report. Contemporary clinical dentistry. 2018 Apr;9(2):309.
Kudo K, Hasegawa H, Sato E, Kaneko T, Ishida D, Kanno C, Endo M. A case of rhinocerebral mucormycosis extending into the skull. Journal of oral and maxillofacial surgery, medicine, and pathology. 2017 Jan 1;29(1):61-4.
Swain SK, Behera IC, Mohanty JN. Mucormycosis in head-and-neck region–Our experiences at a tertiary care teaching hospital of East- ern India. Annals of Indian Academy of Otorhinolaryngology Head and Neck Surgery. 2019 Jul 1;3(2):58.
|
How to cite this article:
|
| ||
|
View the full-text PDF:
|
| ||