Bullous pemphigoid: Case report and review of literature
Shunmugavelu KARTHIK1, Shanmugam ARASU2, Srikanthan SRIRAM3, Evangeline Cynthia DHINAKARAN4, Yalamanchi ANUSHA5, Shenbagasavan Perumal JANANI6, Raghavelu Narendran MUGUNDAN7
1,4,6,7 Dentistry/Oral and Maxillofacial Pathology, Mercy Multispeciality Dental Centre, Chrompet, Chennai, Tamilnadu, India
2 Oral and maxillofacial surgery, Fortis Hospital, Vadapalani, Chennai, Tamilnadu, India
3 Dept of Public Health Dentistry K.S.R. Institute of Dental Science&Research, Tiruchengode, Tamil Nadu
Hellenic Archives of Oral & Maxillofacial Surgery (2021) 2, 125-128
DOI https://dx.doi.org/10.54936/haoms222125128
SUMMARY: Bullous pemphigoid (BP) is an autoimmune bullous disease characterized by subepithelial blistering mostly affecting elderly but may be seen in all ages. A 52-year-old female patient came with a chief complaint of itching, redness and ulcer in the hands and oral cavity for the past 2 weeks. The examination revealed ulcer- ated lesions in palate and buccal mucosa. Erythematous lesions were also seen in upper limb. Incisional biopsy was done and histological examination revealed bullous pemphigoid. The patient was immediately started with systemic and topical steroids and was continued for 3 weeks. The extra-oral lesions were healed and intraoral ulcerations subsided after 3 weeks.
KEY WORDS: Autoimmune bullous disease, ulcerated lesions, steroids.
REFERENCES
1,4,6,7 Dentistry/Oral and Maxillofacial Pathology, Mercy Multispeciality Dental Centre, Chrompet, Chennai, Tamilnadu, India
2 Oral and maxillofacial surgery, Fortis Hospital, Vadapalani, Chennai, Tamilnadu, India
3 Dept of Public Health Dentistry K.S.R. Institute of Dental Science&Research, Tiruchengode, Tamil Nadu
Hellenic Archives of Oral & Maxillofacial Surgery (2021) 2, 125-128
DOI https://dx.doi.org/10.54936/haoms222125128
SUMMARY: Bullous pemphigoid (BP) is an autoimmune bullous disease characterized by subepithelial blistering mostly affecting elderly but may be seen in all ages. A 52-year-old female patient came with a chief complaint of itching, redness and ulcer in the hands and oral cavity for the past 2 weeks. The examination revealed ulcer- ated lesions in palate and buccal mucosa. Erythematous lesions were also seen in upper limb. Incisional biopsy was done and histological examination revealed bullous pemphigoid. The patient was immediately started with systemic and topical steroids and was continued for 3 weeks. The extra-oral lesions were healed and intraoral ulcerations subsided after 3 weeks.
KEY WORDS: Autoimmune bullous disease, ulcerated lesions, steroids.
REFERENCES
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- Bernard, P. and Antonicelli, F., 2017. Bullous pemphigoid: a re- view of its diagnosis, associations and treatment. American journal of clinical dermatology, 18(4), pp.513-528.
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- Ohki, M., Kikuchi, S., Ohata, A., Baba, Y., Ishikawa, J. and Sugimo- to, H., 2016. Features of oral, pharyngeal, and laryngeal lesions in bullous pemphigoid. ENT: Ear, Nose & Throat Journal, 95.
- Kridin, K. and Bergman, R., 2019. Assessment of the prevalence of mucosal involvement in bullous pemphigoid. JAMA derma- tology, 155(2), pp.166-171.
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- Lee, S.G., Lee, H.J., Yoon, M.S. and Kim, D.H., 2019. Association of dipeptidyl peptidase 4 inhibitor use with risk of bullous pemphigoid in patients with diabetes. JAMA dermatol- ogy, 155(2), pp.172-177.
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- De Vega, I.F., Iranzo-Fernández, P. and Mascaró-Galy, J.M., 2014. Bullous pemphigoid: clinical practice guidelines. Actas Dermo-Sifiliográficas (English Edition), 105(4), pp.328-346.
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